Some enemies (like that pesky alien worm) are bullet sponges. One-hit kill means any attack, even a whack with a broken pipe, destroys any threat instantly.
You can edit certain save files (JSON or .cfg) to give yourself massive resource stacks. This requires locating your save directory and manually adjusting numbers—tedious but safe. breathedge trainer
Some versions of Breathedge have an unofficial developer console. You can enable it by editing an .ini file, then type commands like god or giveall. Check the Breathedge subreddit or Steam guides for the current method (as patches often break console access). Some enemies (like that pesky alien worm) are bullet sponges